Review Article

Renal function during exercise and recovery

Javier Calderón Montero*

Published: 01 February, 2019 | Volume 4 - Issue 1 | Pages: 008-015

This review paper analyzes the response of renal function during two types of exercise: 1) exercise of increasing intensity and 2) exercise of submaximal intensity and prolonged duration. During an effort of increasing intensity there is a decrease in renal blood flow that, theoretically, could compromise renal function. However, several studies seem to show that the kidney has self-regulatory mechanisms that allow maintaining the filtration fraction. On the other hand, ultra resistance exercises, such as ironman, are becoming more frequent. Knowing the renal response to this type of exercise is essential to apply knowledge to emergency situations such as dehydration or hyponatremia.

Read Full Article HTML DOI: 10.29328/journal.jsmt.1001037 Cite this Article Read Full Article PDF


  1. Kenney WL, Wilmore J, Costill D. Physiology of sport and exercise 6th edition. Human kinetics. 2015; 648. Ref.: https://goo.gl/fUKyPp
  2. McArdle WD, Katch FI, Katch VL. Exercise physiology: nutrition, energy, and human performance. Lippincott Williams & Wilkins. 2010; Ref.: https://goo.gl/Yrcw8P
  3. Berg U, Bohlin AB, Freyschuss U, Johansson BL, Lefvert AK. Renal function and albumin excretion during exercise in children during remission of the minimal change nephrotic syndrome. Acta Paediatr Scand. 1988; 77: 287-293. Ref.: https://goo.gl/AMytPM
  4. Castenfors J. Renal function during exercise with special reference to exercise proteinuria and the release or renin. Acta Physiol Scand Suppl. 1967; 293: 1-44. Ref.: https://goo.gl/QXmVid
  5. Irving RA, Noakes TD, Burger SC, Myburgh KH, Querido D, et al. Plasma volume and renal function during and after ultramarathon running. Med Sci Sports Exerc. 1990; 22: 581-587. Ref.: https://goo.gl/bJycVs
  6. Poortmans JR. Exercise and renal function. Exerc Sport Sci Rev. 1984; 1: 125-153. Ref.: https://goo.gl/iNRuip
  7. Castenfors J. Renal function during prolonged exercise. Ann N Y Acad Sci. 1977; 301: 151-159. Ref.: https://goo.gl/Xy2qER
  8. Irving RA, Noakes TD, Buck R, van Zyl Smit R, Raine E, et al. Evaluation of renal function and fluid homeostasis during recovery from exercise-induced hyponatremia. J Appl Physiol. 1991; 70: 342-348. Ref.: https://goo.gl/n2AXpo
  9. Irving RA, Noakes TD, Raine RI, Van Zyl Smit R. Transient oliguria with renal tubular dysfunction after a 90 km running race. Med Sci Sports Exerc. 1990; 22: 756-761. Ref.: https://goo.gl/j41VmD
  10. Johansson BL, Berg U, Bohlin AB, Lefvert AK, Freyschuss U. Exercise-induced changes in renal function and their relation to plasma noradrenaline in insulin-dependent diabetic children and adolescents. Clin Sci (Lond). 72: 611-620. Ref.: https://goo.gl/RQdqp5
  11. Zambraski EJ. Renal regulation of fluid homeostasis during exercise. In: In Gisolfi CV, Lamb DR. (eds.) Fluid homeostasis during exercise Carmel Indiana Benchmark Press c1990; 247-280.
  12. Neumayr G, Pfister R, Hoertnagl H, Mitterbauer G, Getzner W, et al. The effect of marathon cycling on renal function. Int J Sports Med. 2003; 24: 131-137. Ref.: https://goo.gl/CjH78K
  13. Neumayr G1, Pfister R, Hoertnagl H, Mitterbauer G, Prokop W, et al. Renal function and plasma volume following ultramarathon cycling. International journal of sports medicine. 2005; 26: 2-8. Ref.: https://goo.gl/jzwukm
  14. Silberberg MS. Chemistry, the molecular nature of matter and change, 3rd ed., McGraw-Hill, Boston, Mass., USA. 2003; 777. Ref.: https://goo.gl/VK1wDD
  15. Johnson RL, Heigenhauser GJ, Hsia CC, Jones NL, Wagner PD. Determinants of gas exchange and acid-base balance during exercise. Handbook of Physiology. Exercise: Regulation and integration of multiple systems. 1996; 515-584. Ref.: https://goo.gl/VaL6v1
  16. Halestrap AP. The monocarboxylate transporter family-structure and functional characterization. IUBMB life. 2002; 64: 1-9. Ref.: https://goo.gl/9rxbDj
  17. Fallo F. Renin-angiotensin-aldosterone system and physical exercise. J Sports Med Phys Fitness. 1993; 33: 306-312. Ref.: https://goo.gl/AN31WA
  18. McKelvie RS, Lindinger MI, Heigenhauser GJ, Sutton JR, Jones NL. Renal responses to exercise-induced lactic acidosis. Am J Physiol. 1989; 257: R102-108. Ref.: https://goo.gl/pHvaQ2
  19. Ishikawa I. [Post-exercise acute kidney failure]. Nippon Naika Gakkai Zasshi. 2005; 94: 1949-1955.
  20. Dann EJ, Gillis S, Burstein R. Effect of fluid intake on renal function during exercise in the cold. Eur J Appl Physiol Occup Physiol. 1990; 61: 133-137. Ref.: https://goo.gl/iPtE2Y
  21. De Moraes R, Gioseffi G, Nóbrega AC, Tibiriçá E. Effects of exercise training on the vascular reactivity of the whole kidney circulation in rabbits. J Appl Physiol. 2004; 97: 683-688. Ref.: https://goo.gl/ft7ZrZ
  22. Fuller JH, Bernauer EM, Adams WC. Renal function, water and electrolyte exchange during bed rest with daily exercise. Aerosp Med. 1970; 41: 60-72. Ref.: https://goo.gl/SkaMh8
  23. Grignolo A, Koepke JP, Obrist P. Renal function, heart rate, and blood pressure during exercise and avoidance in dogs. Am J Physiol. 1982; 242: R482-490. Ref.: https://goo.gl/jJa4TW
  24. McKeever KH. Effect of exercise on fluid balance and renal function in horses. Vet Clin North Am Equine Pract. 1998; 14: 23-44. Ref.: https://goo.gl/FYpHjg
  25. Otani H, Kaya M, Tsujita J. Effect of the volume of fluid ingested on urine concentrating ability during prolonged heavy exercise in a hot environment. J Sports Sci Med. 2013; 12: 197-204. Ref.: https://goo.gl/YZzGrN
  26. Castenfors J. Renal function during exercise. With special reference to exercise proteinuria and the release of renin. Acta Physiol Scand Suppl. 1967; 293: 1-44. Ref.: https://goo.gl/qV3bP3
  27. Freund BJ, Wade CE, Claybaugh JR. Effects of exercise on atrial natriuretic factor. Release mechanisms and implications for fluid homeostasis. Sports Med. 1988; 6: 364-377. Ref.: https://goo.gl/EmntEj
  28. Lichtig C, Levy J, Gershon D, Reznick AZ. Effect of exercise on the kidney of aging mice. Isr J Med Sci. 1989; 25: 376-381. Ref.: https://goo.gl/WvuTN5
  29. Hiraki K, Kamijo-Ikemori A, Yasuda T, Hotta C, Izawa KP, et al. Moderate-intensity single exercise session does not induce renal damage. J Clin Lab Anal. 2013; 27: 177-180. Ref.: https://goo.gl/m1x5HQ
  30. Poortmans JR, Vanderstraten J. Kidney function during exercise in healthy and diseased humans: An update. Sports med. 1994; 18: 419-437. Ref.: https://goo.gl/aQow5M
  31. Grimby G. Renal clearances during prolonged supine exercise at different loads. J Appl Physiol. 1965; 20: 1294. Ref.: https://goo.gl/24cTLh
  32. Smith JH, Robinson S, Pearcy M. Renal responses to exercise, heat, and dehydratation. J Appl Physiol. 1952; 4: 659. Ref.: https://goo.gl/qXKeqV


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